Ok...
I've checked the save. Looks great, but.. quite few things that require fixin'
1. Rome is in horrible state... (just kidding

)
It makes 19gpt and cavalry costs 80... Guess how many shields are wasted at the last turn. Change citizen from FP to mined grassland and rome will make 80gpt... Sell Granary in Rome (sell granaries everywhere we have pyramids), then use our old granary trick... Build granary for one turn, then rush it and switch to Cavalry - we will be getting cavalry from Rome every 2 turns...
I know players from previous game remember this trick suggested by Eldar

we need to repeat it here.
It's time to do better MM here. on DG map AIs will kick our butts if we are not good with MicroManagement.
We need to set citizens in our military production cities in a way to minimize shield waste.
2. We don't need to keep so many fortified cavalry in our southern cities. Send them to the front lines ASAP. ELite horses send those to front lines for leader fishing. We don't need more than one MPs on cities like St. Petersburg or Pompeii and old fashined horse or archer is enough..
3. Another ASAP task -
buy World Map.. That will make it much easier to plan attacks in future.
4. That Gem city we have had so many debates about...

Slave roading gem mountain and will do it for another 13 turns... But worker will be ready in 3 turns, so Gems will be connected sooner.
5. Since we have Pyramids now may be makes sense to shave a round of settlers in each city with exception of Rome (Rome is exception because it is the only city with 20gpt and 2turn cavalry possible production rate). I let us to debate on this one though. Everything above was mandatory.
6. DO NOT BUILD TEMPLES IN CHINESE CITIES YET - RUSH SETTLERS AND FILL THE GAP IN CHINA LAND ASAP.
Domination can be reached much faster if we fill gaps with settlers instead of temples. Settlers are cheaper and more cities give us better unit support. So Switch all the China to settlers and cash rush them. Do not cash rush settlers or any other build for that matter on the first turn you start building them (when you do't have any shields accumulated). It will cost us double - i know everyone knows this but just to stress it again.
We can get 5 settlers from china right away and fill that part of Pangea with cities.
7. Can somebody look at mapstat to check flip probability for celtic cities? They have 8 times as much culture comparing to ours. I don't have map stat on this computer
8. After resistance in entremont is subdued rush settlers before building temple.. That way we starve their cities much faster.
Should we try capture remaining celtic cities??? I am not sure what's better, but if we look what is current flip probability it will give us an idea what's better. Still I would be afraid to keep armies in Entremont for more than turn or two.... Park them outside instead and capture entremont and other celtic cities again as they flip. Each time we recapture them their pop goes down by one... That's another way to starve them.
9. Why would bunch of workers try to clean polluted forest near St. Petersburh when there are whole bunch "clean" unimproved tiles around that city? It takes too long to clean pollution and if we have other tiles to improve always to those.. We are likely to finish this game before we need those "polluted' tiles.
10 Workers are mining hills near Pisae, Hispalis, Vladivostok..

But those cities won't use those hills like in next 30-40 turns or so... Workers should have started irrigating plains instead to maximize pop growth in those towns.
Disclaimer:
Everything i said above is not going to prevent us from winning this game.
But if we follow most of the bullets above we will sure have faster winning date.
