Em, well heres a few pointers:
1. Rush for the Baron - Get him and then you can build an army of werewolves, saving you from having to train them in your cities leaving you to build other things. (Plus he's damn cool!

)
2. Found a religion and spread it, standard rule for vanilla civ too, spreading it to your neighbours drastically reduces the chance of them attacking you.
3. You need regeants for Mages and Archmages etc so make sure you have this resource or can trade for it as you don't want to be missing out on the power of Archmages.
4. You are gonna need to start building your army earlier than in vanilla civ as the barbarians are just crazy, so although you really want to build that settler your not gonna be able to protect him or the city as the barbarians
WILL come in force.
5. Be careful when scouting in the early part of the game as the hill giants are nasty!
Can't remember anything else other than the tech tree is significantly more open than in vanilla civ so research, while being very important, isn't the be all and end all it is in vanilla.