My sister was paying over $1000 a month for her one child at daycare and I thought that was crazy, but they lived in an urban area on the coast. If me and my wife had to pay that much it would be about half of my wife's income. With two kids it would be all of her pay, and with a third one on the way....well she would be getting paid NOT to work. But we live in a lower cost of living area, so licensed daycare costs are typically about $700 a month for fulltime, which is still too high, so luckily our work schedules allow us to not need full time daycare.
I work every weekend and every Monday, she works every other weekend (and other days during the week, where I watch the kids) and has classes on Mondays. No licensed daycare operates on the weekend* tempting my wife to open a daycare that is open on the weekends. So we have to hire a regular babysitter for every other weekend. Then Mondays were a problem, at one time we were able to hire a high school kid for every other weekend, she's wasn't available on Mondays. Licensed daycare places typically don't take children for only one day (unless you pay the 'part time' weekly fee which is about three days worth). But we finally found one that charged $3.50/hour per child, but after we used them for a year they closed down. We will use another one that charges $4/hour per child, which is higher than the weekend babysitter we pay $2.50/hour for ($5 for two kids, next year will be $7.50). A third option was a daycare that charged $50 a day per child for drop offs, which is intended for people who don't regularily use daycare (emergencies, appointments, etc.) but we would always have to check to make sure they had space available, so there isn't a guarantee we would have daycare available on any given week.
*apparently according to the laws around here daycare centers can operate on the weekend, but if they do, they can't operate during the week. It's one or the other, and there is far more demand for Monday-Friday than there is for weekends, so that is why they all only work during the week.
2nd shift, 3rd shift and weekend workers rarely use any licensed daycare.