I haven't noticed any major changes other than a bit of increased ai tech rate (since before I was playing with it set on 15 via mod). I normally play emperor since I can reliably win on that difficulty without much trouble, but the AI isn't horribly behind. Though I'm still on my first game since the patch. I really can only play on my days off and I play marathon. I am using mods, but only ui mods at the moment.
I'm playing Japan and I did do a somewhat early conquest of Portugal. Perhaps I was lucky to not get a strong neighbor. I wasn't planning on it but he DOW me first, so I figured I'd Agoge up and smash him. He was forward settling me anyways. I've been peaceful ever since, I have enough room for all my cities now.
I often go for the 4 policy card increasing wonders, the only one I missed out on was Alhambra, but I normally miss out on that one, usually only get it 25% of the time or so. So 3 out of 4 is normal for me. The new Japan leader is fairly strong I think, so that may help.
One thing I noticed is Rome got industrialization super early. Though even before the patch AI seems to like to get to that tech early. I had no chance at Ruhr Valley.