Hi Winner, nice to have you back
I never had a pet- or rather i did once have one, but i won't go into that

- so i didnt bond with an animal as a child. This certaintly dissallowed me from feeling love for it, but also, probably, made me free of forming childish views of animals as well- not saying that all animal defences are based on childish views.
I have noticed that my view on animals, namely that they can be seen as mere resources, is connected with my overall view of life. You might recall my thread about a quote by Protagoras, according to which the measure of all things is man. From this follows that all values, intrinsic or not, are calculated by man, in regards to his benefit.
This allows us, for example, to claim that eating meat as a meal is good, since it gives us pleasure (if we eat meat and like it), and not worry about question about the animal which was killed.
Although personally i have little use for the cosmetic industry, i accept that there are many people who view it as something very important in their lives. And to dissallow animal testing there (somethign which probably potentially harms the animals in the lab) woudl mean that we would have even less safe products for humans, leading to possible harm for them. Thu again i believe that human health> animal health, nomatter that the cosmetic industry is obviously full of greed and exploits ussually (at least in dramatic cases) the vanity of people, which by itself was harmfull to them.
You mentioned the prospect of creating a human/animal hybrid, or at least some animal with intelligence comprable to our own. Are such experiments currently allowed? Isnt the use of human dna in such cases prohibited?
In my view the creation of such a being would have effects very hard to calculate. We never had an animal as sentient as us live next to us. The alst time when two beings of somewhat comprable intelligence lived on the planet led, i think, to battle between them, and the final demise of one. Of course this would be an isolated case of a superanimal, but if it was sentient enough then wouldnt that harm it? It doesnt seem easy to be the sole member of a species that has human intelligence.
You might recall that i once had met a severely mentally handicapped child, and it was a traumatic experience for me, since i was only 11 years old. At the time i thought that such a child had no rights, due to its obvious diminished existence. However now i think that humans in such states should be protected, sure they are something "lesser" than normal humans, but they have the right to live, and sadly they can only live if they are actively protected by others.
It is not the same case with animals. Animals do not need special treatment, since they are animals to begin with. They seem perfectly happy in farms, i trust. Of course if you think about it it is tragic what happens there, the animal "trusting" the humans, but then all along it was raised so as to be slaughtered.