D0NIMATRIX
Full of drivel
I figured it out (at last). I thought the instructions meant preferences in the program, not system preferences.

Has anyone figured out how much extra it costs to run these? I am mostly concerned with the extra electricity running the cpu and cooling fans.
If you run your computer 24/7 just to fold it will cost you quite a bit more to fold. However if you run it only when your computer is being used the extra costs should be negligible.
Look at how many watts your processor consumes at load, and compare wattage that to a light bulb. You should then have a rough Idea of how much it will cost you to run folding.
I have a desktop and my laptop folding 24/7, and my electric bill for November for my entire apartment was under $30. Really not that bad. To give a few numbers, a Core2 Duo processor is rated at 65 watts, which doesn't mean it uses that all the time, but it's a typical load. Folding will probably add a few watts, lets say 10. 10 watts over 24 hours over a 30 day month = 7.2 kWh, electricity costs around .08/kWh, so you've got less than an extra dollar a month if your computer is already on. Your mileage may vary, but it's a small cost for the benefit science gets.
It's been available for a while. The Mac SMP version came first (for a change), and it's been pretty stable, so I can recommend this option as long as you run a multi-core PC for more than a few hours a day.For Windows users the SMP client is now in Beta testing!
I've downloaded the application again.
I'll be running it a moderate amount, I will also put this program on my new laptop once I go back to school.