The main problem was that I'd have to fight England (for St Johns), France (for Mexico City) and Spain (for Yax Mutal) for the UHV (not the Aztecs of course, cause they're non-European) while having only 2 cities on start.
The polish got kicked out of Prussia by the Prussians so their empire goes from Krakow to Kiev. French got both conquerors but only took Mexico City out of the Aztecs, England decided that South Africa and Australia where way better than NYC or Boston (although I blame that on the French city having to much culture too early).
Basically, I'd say it's the worst start you can get 'cause all the Europeans will still have holdings in your UHV territory after the flip, and you don't have good starting cities like NYC, Boston and Fort Augustine.