We aren't talking early term(for which I will adopt Bill Clinton's safe/legal/rare), and I'm getting the development process of sapience from El_Mac's terms. Which, from what I can tell, are better than anyone else here's knowledge. So I'm not replacing them with inferior versions.
I can remove sapience from the equation. I farm. I've killed a lot of mammals, piecemeal, they possess no human sapience or potential. But they're otherwise mostly the same. Groundhogs, squirrels, deer, mice, opossums, coyotes, racoons, birds: lots of varmits over the years. You can trap or poison them, and it's easier, but then you kill things you didn't intend. So depending on backdrop, birdshot or a .22 is more labor, but less destructive. They all died hard. They all fought. I've watched that hundreds of times, I did it. I watched it happen to the reason I live, too. Tasted the breath. They all die more similarly than they live. The overlap is pretty extreme*. So yeah, I can remove the sapience, if it doesn't matter at all, but it changes my moral calculus on a lot. For example, if I don't care about that much, anymore, I think we should be scratching "made in USA" off our biggest most obsolete dumb bombs and giving them to the only people willing right now to "manage" a longstanding problem population of varmints.
*I'm reminded of a park ranger needing to explain why they don't bear-proof garbage harder when they have a problem with bears getting into garbage. It went something like: "Our garbage recepticles need to be accessible to 100% of humans. The top 20% of bears and the bottom 20% of humans have a lot more in common than you think."