Perhaps a source to include in this mod is the SyFy channel's Sanctaury. It follows a kind of League, about a group of individuals who while attending Oxford in the mid 1800's, procured a sample of vampire blood and injected themselves with it. The leader of the group, Helen Magnus, pretty much became immortal; Druid was able to teleport and went mad becoming Jack the Ripper; Watson's mind increased almost exponentially; Tesla, developed magneto-like pwers and became a pseudo-vampire, and Nigel Griffin was able to become invisible. The show mainly takes place in current day "Old City" and Magnus's drive to find and protect "abnormals," ex: Bigfoot is her manservant (butler/bodygaurd).
Civs would inlcude the Cabal, Vampires, Hollow Earth, a crazy billionare, and the Sanctaury Network.
It doesn't actually use any kind of "steam" power, but a Victorian woman wielding a laser pistol while chasing werewolves with Jack the Ripper come close. Plus, her father was probably the source for Dr. Monroe.