Good news is that current vaccines seem to be still fairly effective in preventing hospitalization and death.
But they may need "fine-tuning" against Omicron. I'm going to need second booster somewhere in February, would prefer it to be updated version already.
Russia has reached 45% fully vaccinated . At least we are moving forward.
New antiviral drug "Mir-19" is being developed in Russia. It uses "Small Interfering RNA" technology (whatever that means) to block virus multiplication.
From what I'm reading, experts are carefully optimistic about it. If it really shows good efficacy, it may be a major breakthrough.
This is a publication from April, after testing the drug on Syrian hamsters.
https://onlinelibrary.wiley.com/doi/full/10.1111/all.14850
Clinical trials are already begun.
Quick biology explanation for siRNA (small interferring RNA):
You remember the mRNA vaccines, that they deliver the construction plan of the spike protein to the cells, so that they produce it on their own, yes?
This is a general biological principle, all proteins in our cell are produced this way, first you get the plan as mRNA, then you get the protein.
siRNA is basically the negative (as in photo negative) of an mRNA. It would bind to the mRNA, and therefore block the protein production (“interferre“ with it) of the virus.
Curious about this one. The technology itself is considered very interesting, but AFAIK medical applications have so far been rather disappointing (pre-Covid, I mean).
Let's hope it works. Could potentialy be cheap, also easily adjustable to new variants, and resistance would not be expected, I think.
Yay, christmas vacation....Got called yesterday and now the kids (and de facto me too) are in quarantine for the rest of the vacation. Fun.
Oh damn, sorry to hear.
I hope you didn't travel anywhere...